Conceptualization and design of natural throat lozenges bearing active components from olive leaf extract

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Xavier Cruz Correia
Bára Pinčáková
Matías Vainstein
Sebastian Nobbe

Abstract

This work presents the conceptualization and design of throat lozenges bearing active components from olive leaf extract as a means of valorizing olive leaves. This novel product is a vegan alternative to conventional lozenges and its natural formulation avoids the adverse effects of amylmetacresol, 2,4-dichlorobenzyl alcohol, and menthol, which are common ingredients of Strepsils® and Halls® lozenges. A reliable and straightforward methodology for the preparation of natural throat lozenges is herein described. Additionally, this product is compatible with the use of other leaf extracts, allowing the expansion and diversification of the production line. The manufacture process was simulated using Aspen Custom Modeler software and the energy required for the production of the lozenges was determined to be 0.28 kWh per kilogram of product. A preliminary economic analysis revealed that the industrial implementation of this product is viable, and the payback time was estimated at 4 years.

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