This special issue of University of Porto Journal of Engineering contains selected papers presented at the 2nd International Conference on Science and Technology Education STE 2021, held at Faculty of Engineering of the University of Porto (FEUP), Portugal, during 7-8 October 2021.

This conference is held every two years. The conference is co-chaired by António Ferreira (University of Porto, Portugal) and Lucas F. M. da Silva (University of Porto, Portugal). The goal of the conference is to provide an international forum for the sharing, dissemination and discussion of research, experience and perspectives across a wide range of teaching and learning issues. About 50 papers were presented by researchers from nearly 20 countries.